The book Principles of Organic Medicinal Chemistry describes the principles and concepts of chemistry, synthetic schemes, structure activity relationships, mechanism of action and clinical uses of carbon compounds in the light of modern trends. The book covers the syllabi of B.Pharmacy and M.Pharmacy courses of all Indian Universities.
This book comprises of 22 chapters. Chapter 1 gives an introduction to medicinal chemistry, Chapter 2 explain about the basics on principles of drug action and physicochemical properties of organic medicinal, substances are elaborated in Chapter 3. The concepts of Prodrugs and Drug metabolism are summarized in Chapter 4 and Chapter 5 respectively. Chapter 6 to Chapter 22 explains chemistry, properties, mechanism of action, structure activity relationships, chemistry of newer drugs and clinical uses of various therapeutic agents. At the end of book, a set of more than 200 essays and short questions and 225 objective questions with answers are strategically designed.

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This is the forth edition of a book written to serve both as a useful textbook for undergraduate courses in medicine and pharmacology, and also as a handy reference title for industry professionals. Each of the 27 chapters is sub-divided into 3 sections: (i) an introduction to the subject, (ii) a chemical or pharmacological classification -– each category of compound importantly contains International Non-proprietory Names (INN), British Approved Names (BAN) and United States Approved Names (USAN) wherever applicable, chemical names and proprietory names. (iii) the synthesis of various important members treated individually, a brief description of the synthesis, therapeutic applications of each compound, the necessary dosage applied in various diseases, and routes of administration. The book also deals well with the comprehensive mechanism of actions of the structure -– activity -– relationships (SARs); thus aiding the students' understanding. Clearly written, well referenced and fully up to date with recommended readings and self assessment questions, Prof. Kar has provided an accessible textbook for students of medicinal chemistry.

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http://rapidshare.com/files/204440704/Medicinal_Chemistry.pdf

Provides a concise introduction to the chemistry of therapeutically active compounds, written in a readable and accessible style.

The title begins by reviewing the structures and nomenclature of the more common classes of naturally occurring compounds found in biological organisms. An overview of medicinal chemistry is followed by chapters covering the discovery and design of drugs, pharmacokinetics and drug metabolism, The book concludes with a chapter on organic synthesis, followed by a brief look at drug development from the research stage through to marketing the final product.

The text assumes little in the way of prior biological knowledge. relevant biology is included through biological topics, examples and the Appendices.

Incorporates summary sections, examples, applications and problems

Each chapter contains an additional summary section and solutions to the questions are provided at the end of the text

Invaluable for undergraduates studying within the chemical, pharmaceutical and life sciences.

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